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ARID (Acute Kidney Injury Risk in Derby) Study

winner arid

For Participants

We would like to express our sincere thanks to all those who have volunteered to participate in the ARID Study.  Your contribution has been invaluable in enabling us to learn more about patients recovery following an Acute Kidney Injury.

Topics covered in this section are: 

where are your kidneys

What is Acute Kidney Injury?

It is an abrupt decline in kidney function.  Acute Kidney Injury (AKI) often occurs as part of other acute illness.  AKI can act as a force multiplier.  This means the effect of the illness symptoms are worse than they might otherwise have been.

Acute Kidney Injury (AKI) continues to be a major priority for Royal Derby Hospital.  This was reflected by the CEO visiting the Medical Assessment Unit (MAU) in April to see the work on quality improvement taking place there.

AKI Research has shown that the correct care after an AKI can improve a patient’s recovery. Therefore, after a hospital stay more information is provided to your GP regarding any AKI episodes.  If appropriate, this should include any changes to your previously recommended medication.

Preparing sample packs
Preparing sample packs

Work continues to collect ARID Study samples. Calls to participants at Year3 will be completed in January 2019. 

Collection of Year5 samples started in February 2018 and will be completed in January 2021. Considering that calls to participants in the ARID Pilot Study started in November 2011, January 2021 now feels like it is not far away…. only two years to go!

Once collected a small amount of the blood and urine samples are frozen and stored at a temperature of -80’C. All the samples are anonymised and labelled with only two unique identifiers and the sample date. Samples are carefully checked and catalogued so that the location of all samples can be found. The sample tubes are less than 4cm in height and stored in boxes of up to 81. Sample maps are required as there are nearly 9,000 samples already in storage from the three time points.

Cataloged samples
Cataloged samples
Checking sample details
Checking sample details
AKI Research has made a difference to standard monitoring for patients suffering an AKI. Royal Derby Hospital has set-up a dedicated clinic for patients most severely affected by AKI. Patients are seen by a kidney doctor after discharge. This initiative has led to further research ideas, including a project to establish whether a Pharmacist can add extra benefit to patient care.

Before May 2017

There have already been some developments based on this and other research in this sector.

[ Zoom ]

Members of the study team are seen here collecting the National Institute of Health Research: East Midlands award in April 2016, left to right: 

Dr Kerry Horne - Research Fellow

Mrs Rebecca Packington - Research Associate

Dr Nick Selby - Associate Professor of Nephrology

Winners - Exceptional Research Delivery

Presented by: Dr Nia Wyn Jones, Associate Professor Obs & Gynaecology

For the main ARID Study

The follow-up period for the main ARID Study has been extended to request samples at 5 years and final follow-up after 10 years.  This is due to the importance of the data obtained to date.  Participants are being asked to consent to the study extension when they are contacted for the third year follow-up.

Data will be reviewed at the end of each time point.  Work is currently underway analysing all the data from participants at the end of the first year after recruitment.  Data will be analysed at the end of the third year, fifth year and finally after ten years!

For the Pilot ARID Study

A final review of the data took place in November 2017.  This is a full 5 years from the end of the Pilot Study recruitment.

Study contact telephone number:         01332 788263

E-mail:   dhft.derbykidneystudies@nhs.net

Please contact us using the above e-mail address for questions about the ARID Study.

In general, we would prefer not to receive queries about your personal health care via this e-mail address.

AKI  Acute Kidney Injury
Not an actual injury but a sudden reduction in kidney function


Chronic Kidney Disease
A gradual decline in kidney function over time

Cohort Study 

A study to which participants are recruited and then data collected over time

As opposed to a

 Cohort Study

A study that analyses data which had been previously collected for a defined group of participants

Retrospective studies have limitations as the subject data is historic and cannot be extended as the study develops.  However Prospective Studies require additional organisation; time has to elapse for the data to be collected and the participant cohort can diminish throughout the duration of the study.

Cohort Group or sub-group of participants in a study

Primary care

Health care provided by your GP in the community

Secondary care

Health care provided by the hospital

Data used in Research is covered by the new UK Data Protection Law, General Data Protection Regulation (GDPR). In relation to the ARID Study the GDPR responsibilities are as follows.

University Hospitals of Derby and Burton NHS Foundation Trust (UHDB) is the sponsor for the ARID Study based in the United Kingdom. We will be using information from you and your medical records in order to undertake this study and will act as the data controller for this study. This means that we are responsible for looking after your information and using it properly. UHDB will keep identifiable information about you for 5 years after the study has finished.

Your rights to access, change or move your information are limited, as we need to manage your information in specific ways in order for the research to be reliable and accurate. If you withdraw from the study, we will keep the information about you that we have already obtained. To safeguard your rights, we will use the minimum personally-identifiable information possible.

You can find out more about how we use your information http://www.derbyhospitals.nhs.uk/research/for-patients-public/your-information/

UHDB will use your name, date of birth, NHS number and contact details (including your address) to contact you about the research study, and make sure that relevant information about the study is recorded for your care, and to oversee the quality of the study. Individuals from UHDB and regulatory organisations may look at your medical and research records to check the accuracy of the research study. The only people in UHDB who will have access to information that identifies you will be people who need to contact you to arrange study visits or audit the data collection process. The people who analyse the information will not be able to identify you and will not be able to find out your name, date of birth, NHS number or contact details.

UHDB will collect information about you for this research study from your medical records. This information will include your name, NHS number/ contact details and health information (including details about hospital admissions), which is regarded as a special category of information. We will use this information to investigate factors that may help us to predict the health outcomes of patients with acute kidney injury (AKI).