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Who's Who

Director: Professor Frances Game

Professor Fran Game, Consultant Diabetologist and Honorary Associate Professor with the University of Nottingham took up the  post of Director of R&D on 1st September 2014.
Prof. Game graduated from the University of Wales and then trained first in Diabetes and then Chemical Pathology in Newcastle and the Midlands. She moved back into Diabetes in 1996 and in 2000 took up a Consultant post at Nottingham University Hospitals NHS Trust. In 2002, she set up the Foot Ulcer Trials Unit with Professor William Jeffcoate. 
Prof. Games' current research includes multi centre trials of the management of diabetic foot ulcers, the effect of renal replacement therapy on the diabetic foot, and the management and outcome of Charcot Foot in Diabetes. She was secretary of the Wound Healing Group of the International Working Group of the Diabetic Foot which produced systematic reviews and guidelines in 2007 and 2011. In May 2011 she moved to take up a new consultant post at Derby Teaching Hospitals NHS Foundation Trust. 

Assistant Director: Dr Teresa Grieve

Head of Clinical Trials and Research Governance: Jo Thornhill

Clinical Trials Contracts Manager: Amy Farmer


Clinical Trials Manager: Rachelle Sherman

Clinical Trials Manager: Kate Frost

Study Support Services Facilitator: Kate Threapleton

Study Support Services Administrator: Pam Ravipati

Pam completed her MSc in Pharmacology at the Glasgow Caledonian University in November 2009, during which she gained an interest in clinical research. She developed the latter by carrying out a clinical research project on the Advantages of the Anti-Inflammatory drug Ginkgo Biloba in Rheumatoid Arthritis at the University of Glasgow. She has gained a number of years’ experience working as a Clinical Trial Co-ordinator in Surrey and then in South London. 

Pam joined the R&D team as Study Support Services Administrator in June 2016 and will be providing administrative support on both commercial and non-commercial trials throughout the study set-up and conduct of the clinical trial.

Quality Assurance Manager: Dr Sarah Skirrow

Sarah completed her PhD in Biomedical Science at the University of Nottingham in Spring 2013 and during this time she gained an insight into running healthy volunteer trials. She decided to further this interest whilst working for the Nottingham University Hospitals NHS Trust as a Research Project Manager and QA Auditor. Over the 2 years that she worked at NUH she gained extensive experience in clinical trial management and developed an interest in quality assurance. 

Sarah joined the Research & Development department at Derby Teaching Hospitals NHS Foundation Trust in August 2016 and will be working to further develop the quality management system within the R&D department.

Principal Research Pharmacist (R&D): Mrs Liz Bedford

Liz is an experienced pharmacist who has worked in many speciailities within the Trust for almost 20 years.  She joined the R&D team in October 2012 but has experienced research within her previous roles, which include clinical lead pharmacist for Cancer services, Programme leader for the MSc Clinical Pharmacy course at Derby University, and clinical lead pharmacist for the Women’s & Childrens division.  Liz leads a team of pharmacists & pharmacy technicians, who manage and provide dedicated specialist pharmacy services to all clinical trials involving investigational medicinal products (CTIMP trials) in the Trust.

Senior Pharmacist (R&D): Kashmira Subramanian

Kashmira joined the Pharmacy team in the R&D Department in June 2014. Prior to this she worked at The Royal Wolverhampton NHS Trust and The University of Wolverhampton as a Clinical Teacher Practitioner.

Her work here, in brief, involves clinically screening trial prescriptions for current studies before they are dispensed for patients, assisting researchers in the set-up and management of new trials and preparation of in-house clinical trials related documentation.  Kashmira is really pleased to be a part of the team and has found working in Clinical Trials to be a challenge, but one that she has thoroughly enjoyed so far.

Head of Medical Statistics and Data Management: Apostolos Fakis

Apostolos joined the Trust as medical statistician in 2005 following the completion of Master in Medical Statistics at University of Lancaster. He is currently undertaking a Doctorate in Health and Social Care Practice with special interest in mixed methods and the application of Structural Equation Modelling to qualitative data.  He has experience of research ethics as he was vice-chair in the Research Ethics Committee (REC).  

Apostolos is an expert reviewer of National Institute Health Research (NIHR) funding programs and has expertise in research design and methodology for developing studies applying for funding. He is also certified by the Association of Clinical Data Management to provide high quality data management in clinical trials of investigational medicinal products.

Medical Statistician: Michael Jones

Michael completed his MSc in Medical Statistics at the University of Leicester in September 2014, during which he gained an interest in survival analysis, methods of handling missing data and meta-analysis. He developed the latter by carrying out a meta-analysis on a research project on obesity and mortality in partnership with the Leicester Diabetes Centre. He also has a BSc in Mathematics from the University of Birmingham and has experience as a Data Manager after working for the international engineering consultancy company, GL Noble Denton. 

Michael joined the Trust in January 2015 and will be providing statistical advice on both clinical and non-clinical trials throughout the design, analysis, data management, conduct and publications stages.

Clinical Trials Data Manager: Dr Victoria Chester

Victoria joined the trust in June 2016 after several years working in data management for global CRO’s.  She has experience working in phase I-IV CTIMPS , specialising in oncology & paediatrics. Prior to working in the industry, Victoria completed a PhD in Biostatistics at Newcastle University, during which she developed a passion for data handling, database design and multivariate modelling.   

Her current role includes: CRF design, the design, user acceptance testing & validation of study databases, query management and database lock for statistical analysis, however, she also has expertise building studies in Medidata RAVE and e-Clinical OS along with numerous data manipulation software packages.

Clinical Trials Data Clerk:  Trusha Mistry

Trusha recently completed her PhD in Cardiovascular Medicine at King’s College London in which she gained experience of working with complex and large sets of data. 

She joined the trust in August 2016 and will be working in data management and performing database validation, data entry and quality control assessments.

Data Quality and Administration Coordinator: Mrs Trish Boateng

Lead Clinical Trials Nurse: Mr Chris Worth

Chris qualified as a Registered General Nurse in 1992. He has worked in many areas including A & E, MAU and Liver Transplants. He has also specialised in cardiac and respiratory medicine in Primary and Secondary Care. Chris joined the R & D Team in April 2015 having come from a Phase 1 trials unit. He is an Independent and Supplementary Nurse Prescriber and has many post registration diplomas. He is currently finishing his MSc in Clinical Education at Edinburgh University. 

Chris is a Lead Clinical Trials Nurses responsible for managing a team of research nurses as well as undertaking his own study workload.

Lead Clinical Trials Nurse: Dr Kathleen Holding

Kathleen qualified as a Registered General Nurse in 1990 and gained a PhD in Microbial and Environmental Science (Biofilms) from the University of Derby and a BSc Hons in Environmental Science while continuing to work as an RGN. She has a diverse background ideally suited to generic research having worked in intensive care, coronary care, emergency department and general medicine before joining Southampton CRF in 2006. Within the CRF she worked as a junior generic research nurse on a wide portfolio of commercial and non-commercial studies including oncology, obesity and respiratory. 

In 2009 Kathleen became a Senior Respiratory Research Nurse in Southampton Respiratory Biomedical research unit where she was involved in developing staff education within research, co-ordinating and setting up numerous respiratory studies including the treatment of biofilms in Cystic fibrosis and developing respiratory specific competencies. 

She joined the generic research team in Derby in 2012 and has recently been appointed one of the Lead Nurses in a time of great change in the National Institute of Health Research Clinical Research Network.

Clinical Trials Nurse: Ms Julie Dockree

Julie qualified as a Registered General Nurse in 1988. She specialized in critical care for 13 years before moving to primary then secondary care before finding her niche in research. She joined the cancer research team in January 2010 to support Haematology studies at Royal Derby Hospital.

Clinical Trials Nurse: Mrs Marie Appleby

Marie qualified as a Registered General Nurse at Nottingham in 1983. Since qualifying she has worked both within primary and secondary healthcare mainly in general medicine with an emphasis on cardiology. In 2004 she worked part time in a nurse led hypertensive service in secondary care under the guidance of a cardiologist helping to manage complicated and difficult to control hypertensive cases. This was also where she developed a keen interest in the field of clinical research. 

She currently works part time as a Clinical Research Nurse supporting research studies in Diabetes, Renal and cardiovascular areas within Derby hospitals. She also works three days a week as a Heart Failure Specialist nurse in Derbyshire Community Health Services


Clinical Trials Nurse: Mrs Alison Booth

Alison has been a nurse for 28 years and has a background in renal nursing and post registration nurse education.  Alison has worked as a research nurse in the rheumatology department at Derby for the past 9 years and has helped to develop the research activity within the department. 

She has also been active within the Local Clinical Research Network as the musculoskeletal Specialist Interest Group coordinator which has involved developing musculoskeletal research across the Trent region. She is currently serving a second term of office as one of our Staff Governors and amongst many other things is ensuring that research has a high profile within the organisation.

Clinical Trials Nurse: Lynsey Havill

Clinical Trials Nurse: Mrs Charlotte Downes

Charlotte qualified in 2000 with a Higher National Diploma in Adult Nursing. She worked for many years within the Oncology Ward and Chemotherapy Department before joining the Oncology Research Department at the Nottingham University Hospital (NUH) City Campus. While working at NUH she completed her BSc Hons degree. 

Since joining the Royal Derby Generic Research Team in February 2012, she has worked within many specialities including Neurology (Parkinson’s and Dementia), Bariatric's and Ophthalmology.

Clinical Trials Nurse: Catherine Addleton

Since completing her nurse training and BSC(Hons)  in 1996 Catherine worked on a variety of Medical Wards and ICU before moving to research 11 years ago. She has worked in GP surgeries on Phase III and IV studies, assisted in setting up Phase II studies with 4 NHS Trusts in the South East of England and Wales, as well as working on a Phase I Clinical Inpatient Unit. 

Catherine joined the research team at the end of August and will be working on the generic team on both commercial and non-commercial studies.

Clinical Trials Nurse: Kelly White

Kelly qualified from Coventry University with a diploma in Adult nursing in 2001 and from there she spent 5 years working in medical assessment.  She then decided to specialise in renal medicine and found it fascinating so she began working on the renal dialysis unit here at the Royal Derby Hospital. During her time in renal, Kelly has primarily worked on the haemodialysis, however, she has also spent some time in other areas including the community dialysis team looking after and training patients on peritoneal dialysis, the renal ward caring for acutely ill patients and was also able to obtain her degree in renal healthcare studies. 

Renal has always been very research active and as a senior nurse, she was supported in performing audits on the unit and was given the opportunity to undertake the HEEM clinical scholar award programme. This gave Kelly an insight into clinical research and allowed her to perform her own research study in her area which has led to some changes in practice.  Seeing how research can be used to change patients experience for the better and improve their outcomes, has led Kelly to pursue a career in research nursing in a specialty that she is passionate about.

Clinical Trials Nurse: Carly McDonald

Carly trained at Burton Hospital via the University of Wolverhampton for DipHE RN Adult branch. She has been qualified for nearly 3 years and previously worked in Cardiology and Interventional Radiology. 

Carly has joined the Research Team as a generic research nurse and along with the generic studies she’s involved with, she has also been assigned to help the Ophthalmology research nurse with Ophthalmic trials.

Clinical Trials Nurse: Nichola Ebanks

Nichola  qualified as a registered nurse from Nottingham University in 2004 with a diploma in Nursing  and is currently working towards her nursing degree.  Since qualifying Nichola has worked  in the Cardiac Catheter suite at the Royal Derby Hospital where she worked with patients having an acute  MI. She also worked on the Coronary Care Unit where she developed her knowledge of caring for the critically ill.  Nichola has assisted in the development of the emergency Cardiac service which now includes working as part of the out  of hours PPCI team and she has had some experience of teaching as she taught  on the Cardiology Foundation course. 

The CVLPRIT was a study which Nichola assisted on and it was after participating in that study that she realised research is the way forward as it strives to find new ways to fight and manage diseases and improve the quality of life for the benefit of all.  Nichola wanted to be a part of that, knowing that research stops us making assumptions and ensures that we have the evidence we need to deliver better care.

Clinical Trials Nurse: Mrs Susan Yates

Susan has worked in research for the last five and half years, predominantly in diabetes and on diabetic foot ulcer trials. Her nursing background is in Accident and Emergency.

Clinical Trials Nurse: Deborah Morgan

Deborah qualified in 1988 after training to be a Registered General Nurse for three years. She has also studied a Master’s degree in Applied Mental Health and she is a qualified Psychotherapist.  She specialised in Intensive Care Unit (ICU), CCU and HDU as a Senior Sister/Clinical Manager at University Hospitals of South Manchester (Withington & Wythenshawe). She specialised further by training for the Advanced Life Support Course and Pain management. She also worked in the ICU Directorate Resus Training Officer in acute pain management and for ICI Zeneca Toxicology Unit as a Senior Sister.

Deborah was CEO of a leading national charity specialising in perinatal mental health. She campaigned and worked with the media/parliament and celebrities to increase the number of psychiatric Mother & Baby Units in the UK and to increase awareness of the condition generally. Specifically, she worked on a national research project for MIND called ‘Out of the Blue’ with Dr Margaret Oates at Nottingham University (2006). This was presented to the Government for the 60th Anniversary of MIND as an organisation.

Clinical Trials Nurse: Mrs Kelly Langston

Kelly graduated from University of Nottingham in 2000 with a diploma in Nursing and she is currently working towards her nursing degree. Since qualifying she has worked in Haematology and Oncology specialities. She was the junior sister on the Oncology ward from 2005 - 2009. She has also worked as an Oncology Research Sister since joining the Clinical Research Network: East Midlands in 2009 working mainly on the Breast Cancer portfolio.

Clinical Trials Nurse: Joanna Grenyer

Joanna Grenyer qualified in 1996 with Diploma of Higher Education in Adult Nursing. She is experienced in general medicine, respiratory medicine and specialising in Haemato-oncology and cancer chemotherapy since 2002. She joined the CTNs team at RDH at the end of 2011, supporting Haemato-oncology trials.

Clinical Trials Nurse: Mrs Vanessa Unsworth

Vanessa qualified as a Registered Paediatric Nurse, after undertaking her Diploma training in 1994. She worked in a variety of clinical settings and completed her BSc (Hons) in Health Care, before working within the Paediatric Research arena. Vanessa worked for the University of Nottingham, as the Astra Charnwood Research Nurse, where she worked on studies focusing on Paediatric pain management and assessment, unlicensed medication and medication errors. She undertook her MPhil on Paediatric pain assessment that led to publishing in a variety of Medical & Nursing Journals and presenting around the UK and abroad. 

 Vanessa has worked for Derby Teaching Hospitals NHS Foundation Trust for over 10 years, as a Lecturer/ Practitioner and her current role as a Paediatric Research Nurse for 7 years, working on wide range of clinical studies involving children, young people and their families.

Clinical Trials Nurse: Ms Karen Simmonds

Karen qualified in 1981 as a Registered General Nurse and currently working towards a nursing degree. Since qualifying, she has worked in medical, surgical, urology and oncology specialities in various nursing roles. She has been in Clinical Research since 2008 as an Oncology Research Sister working on the urology portfolio.

Research Midwife: Ms Elaine Coulborn

Elaine is a qualified midwife and has worked at Royal Derby Hospital since 1985. This is except for a year’s unpaid year off when she worked in the National Women's Hospital Green Lane in Auckland New Zealand. This is the leading Maternity Hospital in New Zealand looking after all high risk pregnancies. She worked in the Maternity Assessment Unit (MAU) where all antenatal women with complications were assessed. 

At Royal Derby Hospital after gaining experience in a rotational post she has worked in Pregnancy Day Care (PDC) which specialises in looking after high risk pregnancies in conjunction with the Fetal Medicine Consultants. Then for a period she worked in Risk and Audit coordinating the successful Clinical Negligence Scheme for Trusts (CNST) level 2 application.

She joined the research team in Derby in 2013 working on clinical trials in the Reproductive, Health and Childbirth. Elaine manages portfolio trials covering infertility, gynaecology, pregnancy and child birth.

Research Health Care Assistant:  Joely Dixey

Joely is a research HCA.  She has previously worked in Medical Outpatients for 4 years. Her role as Clinical Trials HCA is to work alongside and support the research nursing team in both clinical and non clinical practises, and to support with the overall delivery of research.  Some of the clinical tasks are to take patients blood, carry out observations such as blood pressures, weight and height.  She is also going for training to do cannulation and ECG's. 

Research Health Care Assistant:  Ryan Humphries  

Ryan began working in the NHS in 2006.He has undertaken Level 3 National Vocational Qualification (NVQ) in health care. He worked in many areas including community nursing, endoscopy and acute frontline care. He joined the research team in 2013 where he works on both commercial and non-commercial studies with a special interest in Neurology, Surgery, Ophthalmology and Intensive Care. He has undertaken a variety of courses and had a wide range of practical clinical skills.

Clinical Research Practitioner:  Lianne Hufton

Lianne joined the Research and Development Department at the end of January from a Phase 1 clinical trial unit in Nottingham. Her role with the Trust will be both clinical and admin based. She will be assisting with the setup of trials including submitting approvals and facilitating meetings, communicating with trial centres throughout a study, conducting study procedures, identifying patients eligible for studies and providing patient support and liaising with medical staff on all areas of patient care. Lianne is looking forward to the variety and challenges that this role will bring.

Clinical Research Practitioner:  Melody MacGregor

Melody has worked in the NHS since 1989 starting her career at the Queens Medical Centre in Nottingham, where she worked in both the Neo-natal Unit and then in Dermatology as an HCA and completed NVQ level 3 in Health Care in 2000.  She completed a Foundation Degree in Health and Social Care with Distinction at Surrey University in 2012 whilst working at Surrey County Hospital in Ophthalmology.   Melody joined the R&D Department in 2013 with a wide range of clinical and administrative skills. She works in both Adult and Paediatric areas, on commercial and non-commercial studies and has special interest in Bariatric surgery, Paediatrics and Dermatology. 

Melody and Lianne (above) will be the vanguard of this newly introduced Clinical Research Practitioner role.

Clinical Research Practitioner:  Sam Hussain

Sam’s career in research started in 2007 at the University of Leicester, collaborating with Leicester Hospital where she worked as a Research Assistant in the Department of Infection and Immunity.  Here she did an MPhil in looking at Serum Antibody levels in patients with pneumonia. 

She has worked in the NHS since 2011, and started as a Clinical Research Officer at Nottingham City Hospital where she worked in the Respiratory Clinical Trials Unit.  Her research was based on patients with Chronic Obstructive Pulmonary Disease and she recruited patients from primary and secondary care. 

Sam joined the research team in Derby in August 2015 and has a wide range of clinical and academic skills. She is currently involved in several Renal Trials and is enjoying a new challenge.

Clinical Trials Practitioner:  Sue Smith

After completing her PhD at Southampton University, Sue joined Poole Hospital in Dorset working on an analgesia study in the maternity department.  As this study drew to a close, she moved within the hospital to the Oncology Research Team working on haematology and melanoma studies.  

Sue has now joined the Derby R&D team as a Clinical Trials Practitioner working on myeloma and leukaemia studies.

R&D Finance Officer: Mrs Anne Shaw

R&D Clinical Librarian: Miss Jane Surtees

Jane joined the Trust as Clinical Librarian in 2007 following three years postgraduate research in human-computer interaction and information retrieval. She holds a First class honours degree in Information & Library Management. Jane has presented at conferences both nationally and internationally, and is undertaking MSc study at Oxford University on Evidence Based Health Care.

Research Communications Officer and Clinical Trials Administrator: Kathy Brown

Kathy joined the R&D Department in January 2015 but prior to that she has worked at the Trust from 2007 to Dec 2014  in the Medical Education Department at the Royal Derby Hospital.  

In her current post, Kathy provides some administration duties within Research Governance, however, her main role as a Communications Officer means that she deals with many communications activities for the R&D Department. Kathy produces the R&D Newsletter called ”Taking Part in Research”, keeps the R&D webpages updated and facilitates R&D events, both internal and external i.e.,off site.  

One of the main events in the R&D calendar is the International Clinical Trials Day event, which she is responsible for organizing on a yearly basis and she is also at the forefront of promoting research awareness throughout the Trust to members of the public and to the wider health community .