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NICE Technology Appraisals

This is a list of the published NICE technology appraisals. Technology appraisals are recommendations on the use of new and existing medicines and treatments within the NHS.

NICE TAs: 1-20;  21-4041-6061-8081-100101-120121-140141-160161-180181-200201-220221-240;  241-260 261-280; 281-300; 301-320; 321-340 ; 341-360; 381-400; 401-420; 421-440; 461-480

 

NICE TAs 441-460

REF

TITLE                

DHFT Formulary link 

East Midlands Cancer Network link (cancer drugs only) 

TA 441

Daclizumab for treating relapsing-remitting multiple sclerosis

   
TA 442

Ixekizumab for treating moderate to severe plaque psoriasis 

13.5.3 Drugs affecting the immune response

 
TA 443 

Obeticholic acid for treating primary biliary cholangitis 

Via Regional MDT (Nottingham)

 
TA 444 

Afatinib for treating advanced squamous non-small-cell lung cancer after platinum-based chemotherapy (terminated appraisal) 

Not recommended by NICE

 
TA 445

Certolizumab pegol and secukinumab for treating active psoriatic arthritis after inadequate response to DMARDs

10.1.2 - 10.1.4 Corticosteroids, rheumatic disease suppressants, gout 

 

TA 446

Brentuximab vedotin for treating CD30-positive Hodgkin lymphoma



   
TA 447

Pembrolizumab for untreated PD-L1-positive metastatic non-small-cell lung cancer

   
TA 448

Etelcalcetide for treating secondary hyperparathyroidism

   
TA 449

Everolimus and sunitinib for treating unresectable or metastatic neuroendocrine tumours in people with progressive disease

   
TA 450

Blinatumomab for previously treated Philadelphia-chromosome-negative acute lymphoblastic leukaemia

   
TA 451

Ponatinib for treating chronic myeloid leukaemia and acute lymphoblastic leukaemia

   
TA 452

Ibrutinib for untreated chronic lymphocytic leukaemia without a 17p deletion or TP53 mutation (terminated appraisal)

Not recommended by NICE

 
TA 453

Bortezomib for treating multiple myeloma after second or subsequent relapse (terminated appraisal)

Not recommended by NICE

 
TA 454

Daratumumab with lenalidomide and dexamethasone for treating relapsed or refractory multiple myeloma (terminated appraisal)

Not recommended by NICE

 
TA 455

Adalimumab, etanercept and ustekinumab for treating plaque psoriasis in children and young people

   
TA 456

Ustekinumab for moderately to severely active Crohn’s disease after previous treatment

1.5 Treatment of chronic diarrhoeas

 
TA 457

Carfilzomib for previously treated multiple myeloma

   
TA 458

Trastuzumab emtansine for treating HER2-positive advanced breast cancer after trastuzumab and a taxane

   
TA 459

Collagenase clostridium histolyticum for treating Dupuytren's contracture

   
TA 460

Adalimumab and dexamethasone for treating non-infectious uveitis